FIRST REPORT AND MOLECULAR CHARACTERIZATION OF AN ISOLATE OF PAPAYA RINGSPOT VIRUS (PRSV-W) DETECTED IN PUMPKIN IN CUBA

First report and molecular characterization of an isolate of papaya ringspot virus (PRSV-W) detected in pumpkin in Cuba

In this work, a virus isolate collected from squash plants (Cucurbita pepo L.), showing severe symptoms of mosaic and leaf deformation, grown in Cuba, pinnoitettu kasari was analyzed using indicator plants, electron microscopy, and phylogenetic analysis.Plants of Squash, cv.Caserta, inoculated with this virus isolate showed mosaic, leaf distortion

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Real-world use of orphan medicinal products (OMPs) in rare disease (RD) patients: A population-based registry study

Background: Despite calls for the use of real-world data, the rare diseases (RD) treatment landscape suffers from a scarcity of data referred to orphan medicinal products (OMP) use at the population level.Objectives: We aim to describe the characteristics and patterns of utilization of OMP in a sizable group of RD patients globally monitored by an

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